Cheng Jiang Selected Research

methylselenic acid

1/2016	Methylseleninic Acid Superactivates p53-Senescence Cancer Progression Barrier in Prostate Lesions of Pten-Knockout Mouse.
5/2010	Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.
1/2008	Methylseleninic acid inhibits microvascular endothelial G1 cell cycle progression and decreases tumor microvessel density.
8/2005	PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells.
3/2005	Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells.
5/2004	Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription.
10/2002	Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Cheng Jiang Research Topics

Disease

55	Neoplasms (Cancer) 01/2022 - 07/2002
27	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 07/2002
15	Inflammation (Inflammations) 01/2022 - 12/2012
8	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 06/2013
8	Breast Neoplasms (Breast Cancer) 08/2013 - 06/2002
7	Neoplasm Metastasis (Metastasis) 01/2022 - 12/2006
7	Carcinogenesis 01/2022 - 06/2002
6	Infections 01/2022 - 12/2012
5	Obesity 01/2021 - 05/2015
5	Body Weight (Weight, Body) 11/2018 - 03/2009
4	Adenocarcinoma 01/2021 - 09/2015
4	Diabetes Mellitus 01/2019 - 06/2013
3	Neuroendocrine Carcinoma 01/2022 - 12/2016
3	Brain Ischemia (Cerebral Ischemia) 01/2022 - 01/2018
3	Acute Lung Injury 01/2022 - 02/2019
3	Parkinson Disease (Parkinson's Disease) 11/2021 - 01/2020
3	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2020 - 01/2018
3	Disease Progression 01/2020 - 12/2018
3	Fatigue 01/2017 - 01/2015
3	Leukemia 12/2012 - 07/2002
2	Cytokine Release Syndrome 01/2022 - 08/2021
2	Hypertrophy 01/2022 - 01/2017
2	Lung Injury 01/2022 - 10/2021
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2018
2	Drug-Related Side Effects and Adverse Reactions 12/2021 - 11/2019
2	Necrosis 11/2021 - 01/2019
2	Parkinsonian Disorders (Parkinsonism) 11/2021 - 01/2020
2	COVID-19 08/2021 - 12/2020
2	Intervertebral Disc Displacement (Herniated Disc) 04/2021 - 02/2020
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2020
2	Amyloid Plaque 10/2020 - 01/2015
2	Urinary Bladder Neoplasms (Bladder Cancer) 07/2020 - 12/2012
2	Prostatic Intraepithelial Neoplasia 01/2020 - 01/2016
2	Pulmonary Edema 01/2020 - 02/2019
2	Cognitive Dysfunction 12/2018 - 01/2017
2	Cerebral Hemorrhage 12/2018 - 01/2018
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2017 - 01/2016
2	Lung Neoplasms (Lung Cancer) 07/2017 - 12/2012
2	Diabetic Nephropathies (Diabetic Nephropathy) 12/2015 - 01/2015

Drug/Important Bio-Agent (IBA)

14	SeleniumIBA 01/2018 - 10/2002
13	Androgen Receptors (Androgen Receptor)IBA 01/2020 - 01/2006
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2009
9	methaneselenolIBA 01/2016 - 07/2002
8	Pharmaceutical PreparationsIBA 01/2022 - 01/2015
8	decursinIBA 01/2021 - 01/2006
7	AndrogensIBA 01/2020 - 05/2004
7	methylselenic acidIBA 01/2016 - 10/2002
6	Messenger RNA (mRNA)IBA 01/2022 - 03/2009
6	Biomarkers (Surrogate Marker)IBA 11/2021 - 05/2004
6	Ethanol (Ethyl Alcohol)IBA 01/2021 - 01/2006
6	CaspasesIBA 11/2018 - 07/2002
5	Peptides (Polypeptides)IBA 08/2017 - 08/2014
5	Selenium CompoundsIBA 05/2010 - 07/2002
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 07/2017
4	CytokinesIBA 01/2022 - 01/2017
4	TensinsIBA 01/2022 - 08/2005
4	Biological ProductsIBA 05/2021 - 06/2002
4	Indicators and Reagents (Reagents)IBA 02/2019 - 05/2004
4	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 07/2004
4	Amyloid (Amyloid Fibrils)IBA 01/2015 - 06/2013
4	LigandsIBA 04/2011 - 07/2006
4	Selenious Acid (Selenite)IBA 03/2009 - 10/2002
3	LipopolysaccharidesIBA 01/2022 - 02/2019
3	CateninsIBA 01/2022 - 01/2018
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2022 - 01/2016
3	SynucleinsIBA 11/2021 - 01/2020
3	PyranocoumarinsIBA 01/2021 - 09/2015
3	Glucose (Dextrose)FDA LinkGeneric 10/2019 - 05/2015
3	Streptozocin (Streptozotocin)FDA Link 10/2019 - 01/2015
3	Neuroprotective AgentsIBA 12/2018 - 01/2017
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 11/2005
3	Insulin (Novolin)FDA Link 11/2015 - 12/2004
3	Estrogens (Estrogen)FDA Link 01/2007 - 06/2002
2	Therapeutic UsesIBA 01/2022 - 10/2021
2	Cadherins (E-Cadherin)IBA 01/2022 - 01/2018
2	VimentinIBA 01/2022 - 11/2014
2	Bromodeoxyuridine (BrdU)IBA 01/2022 - 03/2009
2	N- (4- ((6,7- dimethoxy- 4- quinolyl)oxy)- 2- methoxyphenyl)- N'- (1- (1,3- thiazole- 2- yl)ethyl)ureaIBA 01/2022 - 01/2020
2	Adenosine-5'-(N-ethylcarboxamide) (NECA)IBA 01/2022 - 12/2016
2	Caspase 3 (Caspase-3)IBA 01/2022 - 11/2021
2	Caspase 8 (Caspase-8)IBA 11/2021 - 07/2006
2	ClusterinIBA 11/2021 - 01/2020
2	Protein Kinases (Protein Kinase)IBA 04/2021 - 10/2002
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 04/2021 - 08/2005
2	LipidsIBA 01/2021 - 01/2016
2	AldehydesIBA 01/2021 - 01/2020
2	Aldehyde DehydrogenaseIBA 01/2021 - 02/2020
2	Cisplatin (Platino)FDA LinkGeneric 07/2020 - 01/2018
2	Histones (Histone)IBA 01/2020 - 04/2011
2	Complement System Proteins (Complement)IBA 01/2020 - 10/2015
2	bufalinIBA 11/2018 - 04/2011
2	isothiocyanic acidIBA 01/2018 - 02/2015
2	Phosphotransferases (Kinase)IBA 01/2016 - 03/2009
2	Methionine (L-Methionine)FDA Link 01/2016 - 07/2002

Therapy/Procedure

17	Therapeutics 01/2022 - 09/2008
14	Chemoprevention 01/2020 - 10/2002
8	Drug Therapy (Chemotherapy) 01/2022 - 07/2004
6	Chinese Traditional Medicine (Traditional Chinese Medicine) 04/2022 - 04/2011
3	Cardiopulmonary Resuscitation (CPR) 04/2015 - 12/2010
2	Artificial Respiration (Mechanical Ventilation) 12/2020 - 01/2017